GPC2-CAR T cells tuned for low antigen density mediate potent
Por um escritor misterioso
Descrição
Pediatric cancers often mimic fetal tissues and express proteins normally silenced postnatally that could serve as immune targets. We developed T cell…
PDF) Preclinical optimization of a GPC2-targeting CAR T-cell therapy for neuroblastoma
IJMS, Free Full-Text
BiCisCAR T cells targeting both GPC2 and CD276 show potent NB
CD276-CAR T cells and Dual-CAR T cells targeting CD276/FGFR4 promote rhabdomyosarcoma clearance in orthotopic mouse models, Journal of Experimental & Clinical Cancer Research
Full article: B7-H3-targeted CAR-T cell therapy for solid tumors
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours
Overcoming on-target, off-tumour toxicity of CAR T cell therapy for solid tumours. - Abstract - Europe PMC
JCM, Free Full-Text
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion - eBioMedicine
Frontiers CAR T Cell Therapy for Neuroblastoma
Vaccines, Free Full-Text
Development of GPC2-directed chimeric antigen receptors using mRNA for pediatric brain tumors
GPC2-CAR T cells tuned for low antigen density mediate potent activity against neuroblastoma without toxicity - ScienceDirect
Improving CAR-T immunotherapy: Overcoming the challenges of T cell exhaustion - eBioMedicine
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