Viruses, Free Full-Text
Por um escritor misterioso
Descrição
During the Zika virus (ZIKV) outbreak and after evidence of its sexual transmission was obtained, concerns arose about the impact of the adverse effects of ZIKV infection on human fertility. In this study, we evaluated the clinical-laboratory aspects and testicular histopathological patterns of pubertal squirrel monkeys (Saimiri collinsi) infected with ZIKV, analyzing the effects at different stages of infection. The susceptibility of S. collinsi to ZIKV infection was confirmed by laboratory tests, which detected viremia (mean 1.63 × 106 RNA copies/µL) and IgM antibody induction. Reduced fecal testosterone levels, severe testicular atrophy and prolonged orchitis were observed throughout the experiment by ultrasound. At 21 dpi, testicular damage associated with ZIKV was confirmed by histopathological and immunohistochemical (IHC) analyses. Tubular retraction, the degeneration and necrosis of somatic and germ cells in the seminiferous tubules, the proliferation of interstitial cells and an inflammatory infiltrate were observed. ZIKV antigen was identified in the same cells where tissue injuries were observed. In conclusion, squirrel monkeys were found to be susceptible to the Asian variant of ZIKV, and this model enabled the identification of multifocal lesions in the seminiferous tubules of the infected group evaluated. These findings may suggest an impact of ZIKV infection on male fertility.
Which explanation does the nurse know best describes the
Monkeypox
A Brief History of Computer Viruses & What the Future Holds
Coronavirus
Coxsackie B viruses and myalgic encephalomyelitis. - Abstract
DiedSuddenly on X: Study shows that the Covid 19 Vaccine is RE
Ebola
Computer viruses and data protection : Burger, Ralf : Free
Endpoint Detection and Response, Free - What is EDR Security?
de
por adulto (o preço varia de acordo com o tamanho do grupo)