Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers
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![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/305709970/figure/fig7/AS:391715681783823@1470403704636/Clozapine-based-homobivalent-ligands-1a-1f-2a-2-g-and-3a-3-g-22.png)
Clozapine-based homobivalent ligands 1a–1f, 2a–2 g and 3a–3 g [22]
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.frontiersin.org/files/Articles/1038874/fendo-13-1038874-HTML/image_m/fendo-13-1038874-g001.jpg)
Frontiers Modulating brain integrative actions as a new perspective on pharmacological approaches to neuropsychiatric diseases
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://pub.mdpi-res.com/ijms/ijms-24-08656/article_deploy/html/images/ijms-24-08656-g004.png?1683890133)
IJMS, Free Full-Text
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/337114788/figure/fig3/AS:959554447745027@1605787016235/NTS1R-D2R-bivalent-ligand-induced-calcium-release-in-HT22-cells-a-The-applied-bivalent.png)
NTS1R-D2R bivalent ligand induced calcium release in HT22 cells. (a)
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://media.springernature.com/full/springer-static/image/art%3A10.1038%2Fnpp.2013.148/MediaObjects/41386_2014_Article_BFnpp2013148_Fig1_HTML.jpg)
Heteromeric Dopamine Receptor Signaling Complexes: Emerging Neurobiology and Disease Relevance
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://pubs.acs.org/cms/10.1021/acschembio.0c00895/asset/images/medium/cb0c00895_0006.gif)
Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://onlinelibrary.wiley.com/cms/asset/f957a84a-e26d-456c-991b-a6429ad8d864/med.v43.1.cover.jpg?trick=1699879609860)
Recent advances in dopamine D2 receptor ligands in the treatment of neuropsychiatric disorders - Juza - 2023 - Medicinal Research Reviews - Wiley Online Library
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/305678396/figure/fig5/AS:391304828735495@1470305749669/Functional-investigation-cAMP-accumulation-for-representative-ligands-Functional.png)
Functional investigation (cAMP accumulation) for representative
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/297897940/figure/fig1/AS:339512908632064@1457957593478/Illustration-of-the-complexity-of-the-balance-between-A2A-D2R-heteroreceptor-and.png)
Illustration of the complexity of the balance between A2A–D2R
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/profile/Lei-Shi-51/publication/6146371/figure/fig1/AS:394678756233220@1471110156946/Cross-linking-of-D2R-to-a-homodimer-by-copper-phenanthroline-A-treatment-of-FLAG-D2R.png)
Cross-linking of D2R to a homodimer by copper phenanthroline . A
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/259987412/figure/fig4/AS:669647833673761@1536667893948/figure-fig4_Q320.jpg)
Schematic model, showing dynamic equilibrium of the class-A GPCR
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/publication/11965612/figure/fig2/AS:394628332310530@1471098134456/Coimmunoprecipitation-of-D-2-and-D-3-receptors-FLAGtagged-D-2-and-HA-tagged-D-3.png)
Coimmunoprecipitation of D 2 and D 3 receptors. FLAGtagged D 2 and
![Homobivalent Dopamine D2 Receptor Ligands Modulate the Dynamic Equilibrium of D2 Monomers and Homo- and Heterodimers](https://www.researchgate.net/profile/Siegfried-Weisenburger/publication/308038919/figure/fig5/AS:405897697349644@1473784960808/Transient-dimer-formation-of-SNAP-D2L-receptors-a-48-sequential-frames-of-two.png)
Transient dimer formation of SNAP-D2L receptors.: (a) 48 sequential
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